I am currently working on contributing code to create a multi-threaded version of a piece of bioinformatics software I use heavily, Cutadapt. Cutadapt is a Python program that reads through records in a FASTQ file (or pair of FASTQ files) and performs adapter and quality trimming, so the architecture of the program is “read sequentially from one or more files, modify the data, and write the results to one or more output files.